Endogenous ADP-Ribosylation

The natural history of ADP-ribosyltransferases and the ADP ribosylation system.- Identification and Analysis of ADP-ribosylated Proteins.- Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine.- Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein.- Regulation of nitrogenase by reversible mono-ADP-ribosylation.- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.- Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family.- Function and regulation of the mono-ADP-ribosyltransferase ARTD10.- Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-?1 mono-ADP-ribosylation by ARTD15.

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• Imunologia
• Farmacologia
• Microbiologia e virologia médicas

ADP-ribosylated proteins;ADP-ribosylating toxins;ADP-ribosylation;ARTD/PARP family;Endogenous ADP-ribosyltransferase relatives;Mono-ADP-ribosyltransferase;Photorhabdus luminescens toxins;Regulatory T cells;Toxin-neutralizing drugs