Immunopharmacogenomics

PART I TECHNOLOGIES.- 1 Deep Sequencing of T-Cell and B-Cell Receptors with Next-Generation DNA Sequencers.- 2 A TCR Sequence Data Analysis Pipeline: Tcrip.- PART II APPLICATIONS.- 3 Prediction of Drug-Induced Adverse Reactions: Skin Hypersensitivity and Liver Toxicity.- 4 Selection and Monitoring of Patients for Immunotherapy (Peptide Vaccines).- 5 Patient Selection and Monitoring for Immunotherapies: Challenges for Immune Checkpoint Antibody and Cell Therapies.- 6 Better Understanding of Rejection After Organ Transplantation.- 7 Better Understanding of Severe Immunological Reactions: Autoimmune Diseases.- 8 Better Understanding of Severe Immunological Reactions: Food Allergy.- 9 Immune Microenvironment to Predict Response of Cancer Chemotherapy and Radiotherapy.- PART III CHALLENGES AND FUTURE.- 10 Challenges and Future Directions of Immunopharmacogenomics.

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• Farmacologia
• Genética médica
• Oncologia
• Pesquisa médica

Autoimmune disease;BCR;Cancer therapy;Checkpoint inhibitor;Food allergy;HLA;Immunogenomics;Immunotherapy;T-cell repertoire;TCR